J. T. Andersen

NNV024, a novel humanized anti-CD37 antibody with enhanced ADCC and prolonged plasma half-life in human FcRn transgenic mice for treatment of NHL

This paper develops NNV024, a humanized anti-CD37 antibody with enhanced ADCC and prolonged plasma half-life, showing improved efficacy against NHL and CLL cells compared to existing therapies.

Phage display assisted discovery of a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library

The paper discovers a pH-dependent anti-alpha-cobratoxin antibody from a natural variable domain library without histidine doping, showing that pH-dependency can arise without histidine residues.

Titers of antibodies the receptor-binding domain (RBD) of ancestral SARS-CoV-2 are predictive for levels of neutralizing antibodies to multiple variants

This study shows that anti-RBDwt titers correlate with neutralizing antibody levels against multiple SARS-CoV-2 variants and proposes a method to improve immunomonitoring precision and throughput.

In silico proof of principle of machine learning-based antibody design at unconstrained scale

This paper demonstrates that deep generative models can design high-affinity, developable antibodies at scale using synthetic data and transfer learning.