Author

Rajesh Sarkar

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Ashley M. SidebottomiD· 1 shared Hardik ShahiD· 1 shared Jie Du· 1 shared Lei Wang· 1 shared Li YiD· 1 shared Lu GaoiD· 1 shared Matthew Odenwald· 1 shared Mengjie CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Ashley M. SidebottomORCID

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1 paper

Recent·Most cited

Gut Microbiota-derived Acetate Safeguards the Colonic Epithelial Acetyl-CoA Reserve to Avert Colonic Senescence

Jie Du, Rajesh Sarkar, Lei Wang, Roya AminiTabrizi, Lu Gao, Li Y, Ashley M. Sidebottom, Hardik Shah, Mengjie Chen, Matthew Odenwald, Yan Chun Li

The paper shows that acetate from gut microbiota maintains acetyl-CoA levels in colonic epithelial cells, preventing age-independent senescence and inflammation.

bioRxiv · May 19, 2026 · PreprintPhysiology