Cancer BiologyMolecular Therapy — OncolyticsPeer-reviewed
Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells
Chiara Francesca Magnani, Renier Myburgh, Silvan Brunn…·Markus Gabriel Manz
This study develops anti-CD117 CAR T cells with a safety switch to target and eliminate acute myeloid leukemia and hematopoietic stem cells in preclinical models.