Csaba Miskey

This study investigates how ICAA affects HBV-induced gene expression and apoptotic signaling in HepAD38 cells, finding it reverses transcriptional dysregulation and promotes apoptosis.

This study identifies p1/s1, a 3'-nucleotidase/nuclease in Leishmania major, which helps the parasite evade host immune responses by generating adenosine and degrading neutrophil extracellular traps.

This study compares antiviral and cytolytic responses in primary human hepatocytes to YFV vaccine and virulent strains, finding similar propagation kinetics but distinct transcriptional responses.

TSniffer identifies RNA editing sites and quantifies editing activity in RNA-seq data, revealing widespread ADAR-mediated editing in mammals.

This study identifies cell culture adaptive mutations in HCV that enhance replicative fitness in cell lines but reduce virion production in primary human hepatocytes by boosting antiviral responses.

This study identifies HTLV-1 splice sites in gene vectors causing splicing perturbations in transgenic human cells and shows that modifying these sites can enhance genomic safety without compromising therapeutic efficacy.

This paper demonstrates CRISPR/Cas9-guided targeting of Sleeping Beauty transposition in human cells to achieve specific and efficient gene insertion.