Cell BiologyNature CommunicationsPeer-reviewed
Mitochondrial protein heterogeneity stems from the stochastic nature of co-translational protein targeting in cell senescence
Abdul Haseeb Khan, Xuefang Gu, Rutvik J. Patel…·Tatsuhisa Tsuboi
This study shows that mitochondrial fragmentation increases protein expression noise due to stochastic co-translational targeting, and that fission-fusion processes reduce this heterogeneity.
19 citations