Author

Xuefang Gu

Tsinghua Shenzhen International Graduate SchoolORCID 0009-0001-8513-9057Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Tatsuhisa TsuboiiD· 2 shared Abdul Haseeb KhaniD· 1 shared Aidan I. BrowniD· 1 shared Brian M. ZidiD· 1 shared Dexin Shen· 1 shared Matheus Palhares VianaiD· 1 shared Prabha ChuphaliD· 1 shared Rutvik J. Patel· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Tatsuhisa TsuboiORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 8, 2025

A nucleation distance sets the cell size-dependent P-body assembly

Xuefang Gu, Dexin Shen, Xing Quan, Tatsuhisa Tsuboi

The paper investigates how cell size affects P-body assembly in yeast, finding a nucleation distance of 2.2 micrometers that links cell geometry to condensate formation.

DOI 10.1101/2025.07.08.663506

yeastfluorescence / live-cell microscopy

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Cell BiologyNature CommunicationsPeer-reviewedSep 27, 2024

Mitochondrial protein heterogeneity stems from the stochastic nature of co-translational protein targeting in cell senescence

Abdul Haseeb Khan, Xuefang Gu, Rutvik J. Patel…·Tatsuhisa Tsuboi

This study shows that mitochondrial fragmentation increases protein expression noise due to stochastic co-translational targeting, and that fission-fusion processes reduce this heterogeneity.

19 citations

humanproteomics

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