Author

S. A. Zaver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

J. J. Woodward· 4 shared J. L. Hyde· 2 shared J. Schwerk· 2 shared R. Savan· 2 shared A. E. L. Stone· 1 shared A. Forero· 1 shared A. J. Pollock· 1 shared A. M. Kell· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

J. J. Woodward

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

STING activation depends on ACBD3 and other phosphatidylinositol 4-phosphate-regulating proteins

R. D. Luteijn, S. R. van Terwisga, J. E. Ver Eecke, L. Onia, S. A. Zaver, J. J. Woodward, D. H. Raulet, F. J. van Kuppeveld

This study identifies ACBD3 and PI4P-regulating proteins as essential for STING activation and shows that modulating PI4P levels can enhance STING signaling and cytokine production.

bioRxiv · Oct 17, 2022 · PreprintImmunology

Sequence diversity in the 3' untranslated region of alphavirus modulates IFIT2-dependent restriction in a cell type-dependent manner

S. E. Hickson, E. Brekke, J. Schwerk, I. Salukhe, S. A. Zaver, J. J. Woodward, R. Savan, J. L. Hyde

This study shows that variability in the 3UTR of VEEV modulates IFIT2-dependent restriction, with differential sensitivity observed in vitro.

bioRxiv · Dec 10, 2021Microbiology

Endomembrane targeting of human OAS1 p46 augments antiviral activity

F. W. Soveg, J. Schwerk, N. S. Gokhale, K. Cerosaletti, J. R. Smith, E. Pairo-Castineira, A. M. Kell, A. Forero, S. A. Zaver, K. Esser-Nobis, J. Roby, T.-Y. Hsiang, S. Ozarkar, J. M. Clingan, E. T. McAnarney, , R. Savan

This study shows that the OAS1 p46 isoform, targeted to the endomembrane system, enhances antiviral activity against RNA viruses and is associated with COVID-19 severity.

bioRxiv · Apr 21, 2021Immunology

A rationally designed c-di-AMP FRET biosensor to monitor nucleotide dynamics

A. J. Pollock, P. H. Choi, S. A. Zaver, L. Tong, J. J. Woodward

This paper designs a FRET biosensor, CDA5, to detect c-di-AMP dynamics in bacteria, showing unimodal distribution and response changes in mutants.

bioRxiv · Feb 10, 2021 · PreprintBioengineering