Cell BiologybioRxivPreprint
Transforming growth factor-beta signaling via ALK1 and ALK5 regulates distinct functional pathways in vein graft intimal hyperplasia
A. Bradshaw, E. Low, J. T. Schwartze…·A. H. Baker
This study shows TGF{beta} signals through ALK1 and ALK5 in vein graft SMCs, with ALK5 promoting contractility and ALK1 driving migration, suggesting balancing these pathways could prevent graft failure.