Author

C. Delles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

A. Bradshaw· 1 shared A. H. Baker· 1 shared A. Kurkiewicz· 1 shared A. R. Harvey· 1 shared A. Shaw· 1 shared C. J. Schofield· 1 shared D. Kelly· 1 shared D. M. Wall· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. Bradshaw

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Microbiome-derived metabolites reproduce the mitochondrial dysfunction and decreased insulin sensitivity observed in type 2 diabetes

M. J. Ormsby, H. Hulme, V. H. Villar, G. Hamm, G. Rodriguez-Blanco, R. A. Bragg, N. Strittmatter, C. J. Schofield, C. Delles, I. P. Salt, S. Tardito, R. Burchmore, R. J. A. Goodwin, D. M. Wall

The paper identifies two microbiome-derived metabolites, 3M-4-TMAB and 4-TMAP, that induce mitochondrial dysfunction and reduced insulin sensitivity in human liver cells, linking gut microbiota to type 2 diabetes.

bioRxiv · Aug 2, 2020 · PreprintMicrobiology

Transforming growth factor-beta signaling via ALK1 and ALK5 regulates distinct functional pathways in vein graft intimal hyperplasia

A. Bradshaw, E. Low, J. T. Schwartze, A. Kurkiewicz, M. Pek, D. Kelly, A. Shaw, M. Thorikay, J. McClure, M. McBride, S. Arias-Rivas, S. E. Francis, N. Morrell, C. Delles, P. Herzyk, , A. H. Baker

This study shows TGF{beta} signals through ALK1 and ALK5 in vein graft SMCs, with ALK5 promoting contractility and ALK1 driving migration, suggesting balancing these pathways could prevent graft failure.

bioRxiv · Nov 29, 2019 · PreprintCell Biology

Dye-free retinal angiography using blood-oxygenation modulation

L. E. MacKenzie, T. R. Choudhary, J. Fernandez Ramos, N. Benjamin, C. Delles, A. R. Harvey

This paper introduces a non-invasive retinal angiography technique using blood-oxygenation modulation, producing results similar to traditional fluorescence angiography without associated risks.

bioRxiv · Dec 6, 2018 · PreprintBiophysics