Author

S. Atwell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. A. Kossiakoff· 1 shared A. Pustilnik· 1 shared A. U. Singer· 1 shared C. Caseys· 1 shared C. Ho· 1 shared D. J. Kliebenstein· 1 shared D. Kliebenstein· 1 shared D. Y. Mao· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperBiochemistry

A. A. Kossiakoff

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Engineered Antigen-Binding Fragments for Enhanced Crystallisation of Antibody:Antigen Complexes

H. A. Bruce, A. U. Singer, E. V. Filippova, L. L. Blazer, J. J. Adams, L. Enderle, M. Ben-David, E. H. Radley, D. Y. Mao, V. Pau, S. Orlicky, F. Sicheri, I. Kourinov, S. Atwell, A. A. Kossiakoff, S. S. Sidhu

This study identifies surface substitutions that enhance the crystallisation of Fab:antigen complexes by combining surface entropy reduction with phage-display technology and previously reported substitutions.

bioRxiv · Jul 6, 2023 · PreprintBiochemistry

Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing

S. Atwell, R. Lieu, S. Antonysamy, Z. Druzina, C. Ho, R. N. Kang, A. Pustilnik, J. Wang

This study identifies a structural element in rabbit Fab light chains that hinders human Fab crystallization and presents a modified 'Crystal Kappa' design to improve crystallization efficiency.

bioRxiv · Apr 14, 2020Immunology

Quantitative interactions drive Botrytis cinerea disease outcome across the plant kingdom

C. Caseys, G. Shi, N. Soltis, R. Gwinner, J. Corwin, S. Atwell, D. Kliebenstein

The paper investigates how Botrytis cinerea interacts with diverse plant hosts, finding that host species and pathogen strain differences are major sources of variation in disease outcomes.

bioRxiv · Feb 6, 2020Plant Biology

Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana - Botrytis cinerea pathosystem

N. E. Soltis, W. Zhang, J. A. Corwin, S. Atwell, D. J. Kliebenstein

The paper investigates how genetic variation in Botrytis cinerea affects transcriptomes of both the pathogen and Arabidopsis thaliana, identifying trans-eQTL hotspots linked to virulence mechanisms.

bioRxiv · Mar 21, 2019Plant Biology