Author

S. Orlicky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

F. Sicheri· 2 shared A. A. Kossiakoff· 1 shared A. U. Singer· 1 shared D. Y. Mao· 1 shared E. H. Radley· 1 shared E. V. Filippova· 1 shared H. A. Bruce· 1 shared I. Kourinov· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

F. Sicheri

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Engineered Antigen-Binding Fragments for Enhanced Crystallisation of Antibody:Antigen Complexes

H. A. Bruce, A. U. Singer, E. V. Filippova, L. L. Blazer, J. J. Adams, L. Enderle, M. Ben-David, E. H. Radley, D. Y. Mao, V. Pau, S. Orlicky, F. Sicheri, I. Kourinov, S. Atwell, A. A. Kossiakoff, S. S. Sidhu

This study identifies surface substitutions that enhance the crystallisation of Fab:antigen complexes by combining surface entropy reduction with phage-display technology and previously reported substitutions.

bioRxiv · Jul 6, 2023 · PreprintBiochemistry

SCF-FBXW7 regulates G2-M progression through control of CCNL1 ubiquitination

S. O'Brien, S. Kelso, Z. Steinhart, S. Orlicky, M. Mis, Y. Kim, S. Lin, F. Sicheri, S. Angers

This study identifies CCNL1 as a new substrate of SCF-FBXW7 and shows its role in regulating G2-M progression through ubiquitination, revealing a potential therapeutic target in cancer.

bioRxiv · Sep 26, 2022Cancer Biology