Author

C. Ho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Ecology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

D. Harris· 2 shared F. J. Salguero· 2 shared H. E. Humphries· 2 shared K. A. Ryan· 2 shared S. Sharpe· 2 shared Y. Hall· 2 shared A. Abrahamyan· 1 shared A. C. Telfer· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

D. Harris

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Chemotherapy Signatures Map Evolution of Therapy-Related Myeloid Neoplasms

B. T. Diamond, B. Ziccheddu, K. H. Maclachlan, J. Taylor, E. Boyle, J. Arrango Ossa, J. T. Jahn, M. Affer, T. M. Totiger, D. G. Coffey, J. Watts, S. X. Lu, N. Bolli, K. Bolton, J. H. Park, , F. Maura

The paper reconstructs the evolutionary history of therapy-related myeloid neoplasms using chemotherapy-associated mutational signatures and identifies distinct mutational patterns linked to different chemotherapies.

bioRxiv · Apr 26, 2022 · PreprintCancer Biology

mRNA vaccine CVnCoV protects non-human primates from SARS-CoV-2 challenge infection

S. Rauch, K. E. Gooch, Y. Hall, F. J. Salguero, M. J. Dennis, F. V. Gleeson, D. Harris, C. Ho, H. E. Humphries, S. Longet, D. Ngabo, J. Paterson, E. L. Rayner, K. A. Ryan, S. Sharpe, , M. W. Carroll

This study shows that the mRNA vaccine CVnCoV protects non-human primates from SARS-CoV-2 infection and reduces disease severity.

bioRxiv · Dec 23, 2020 · PreprintImmunology

Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques

K. R. Bewley, K. E. R. Gooch, K. M. Thomas, S. R. Longet, N. Wiblin, L. Hunter, K. Chan, P. Brown, R. A. Russell, C. Ho, G. Slack, H. E. Humphries, L. Alden, L. Allen, M. Aram, , M. Carroll

This study evaluates vaccine-enhanced disease in ferrets and rhesus macaques after formalin-inactivated SARS-CoV-2 vaccination, finding mild transient lung pathology but no significant enhancement.

bioRxiv · Dec 21, 2020Pathology

Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing

S. Atwell, R. Lieu, S. Antonysamy, Z. Druzina, C. Ho, R. N. Kang, A. Pustilnik, J. Wang

This study identifies a structural element in rabbit Fab light chains that hinders human Fab crystallization and presents a modified 'Crystal Kappa' design to improve crystallization efficiency.

bioRxiv · Apr 14, 2020Immunology

Interleukin-4 signaling plays a major role in urogenital schistosomiasis-associated bladder pathogenesis

E. Mbanefo, C.-L. Fu, C. Ho, L. Le, K. Ishida, M. Hsieh

This study shows IL-4 signaling is critical for bladder pathology in urogenital schistosomiasis, with IL-4 promoting urothelial proliferation and cell cycle changes.

bioRxiv · Aug 24, 2019Immunology

A reference library for the identification of Canadian invertebrates: 1.5 million DNA barcodes, voucher specimens, and genomic samples

J. R. deWaard, S. Ratnasingham, E. V. Zakharov, A. V. Borisenko, D. Steinke, A. C. Telfer, K. H. J. Perez, J. E. Sones, M. R. Young, V. Levesque-Beaudin, C. N. Sobel, A. Abrahamyan, K. Bessonov, G. Blagoev, S. L. deWaard, , P. D. N. Hebert

The paper provides DNA barcodes for 1.5 million Canadian invertebrate specimens to improve taxonomic identification and biodiversity research.

bioRxiv · Jul 14, 2019 · PreprintEcology