Author

S. Berto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

B. Granger· 2 shared A. A. de Cubas· 1 shared A. C. Crouch· 1 shared B. Gao· 1 shared C. A. Bowers· 1 shared C. Andreani· 1 shared C. Bartolacci· 1 shared C. Behrens· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

B. Granger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-nucleus and spatial landscape of the sub-ventricular zone in human glioblastoma

Y. Licon-Munoz, V. Avalos, S. Subramanian, B. Granger, F. Martinez, S. Varela, D. Moore, E. Perkins, M. Kogan, S. Berto, M. O. Chohan, C. A. Bowers, S. G. M. Piccirillo

The paper builds a single-nucleus RNA-sequencing landscape of the SVZ in GBM patients and identifies therapeutic targets in the T_SVZ microenvironment.

bioRxiv · Apr 24, 2024Cancer Biology

High affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells

R. W. Cochrane, R. A. Robino, B. Granger, E. Allen, S. Vaena, M. J. Romeo, A. A. de Cubas, S. Berto, L. M. R. Ferreira

This study shows that high-affinity CAR signaling in human Tregs leads to increased cytotoxicity and inflammatory cytokine production, while lower affinity reduces these effects.

bioRxiv · Mar 31, 2024Immunology

Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer

C. Bartolacci, C. Andreani, G. Dias do Vale, S. Berto, M. Melegari, A. C. Crouch, D. L. Baluya, G. Kemble, K. Hodges, J. Starrett, K. Politi, S. L. Starnes, D. Lorenzini, M. G. Raso, L. Solis Soto, , P. P. Scaglioni

This study identifies FASN as a therapeutic target in KRAS-mutant lung cancer by showing its role in lipid metabolism and ferroptosis induction.

bioRxiv · Mar 18, 2021Cancer Biology

Accelerated evolution of oligodendrocytes in human brain

S. Berto, I. Mendizabal, N. Usui, K. Toriumi, P. Chatterjee, C. Douglas, C. Tamminga, T. Preuss, S. Yi, G. Konopka

The paper compares gene expression evolution in neurons and oligodendrocytes across humans, chimpanzees, and rhesus macaques, finding accelerated evolution in oligodendrocytes linked to schizophrenia.

bioRxiv · Apr 12, 2019Evolutionary Biology