Author

F. Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

R. Navarro· 2 shared S. Ambros· 2 shared S. F. Elena· 2 shared A. Butkovic· 1 shared A. Lin· 1 shared B. Granger· 1 shared B. Hu· 1 shared B. S. Konigheim· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

R. Navarro

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single-nucleus and spatial landscape of the sub-ventricular zone in human glioblastoma

Y. Licon-Munoz, V. Avalos, S. Subramanian, B. Granger, F. Martinez, S. Varela, D. Moore, E. Perkins, M. Kogan, S. Berto, M. O. Chohan, C. A. Bowers, S. G. M. Piccirillo

The paper builds a single-nucleus RNA-sequencing landscape of the SVZ in GBM patients and identifies therapeutic targets in the T_SVZ microenvironment.

bioRxiv · Apr 24, 2024Cancer Biology

Defects in plant immunity modulate the rates and patterns of RNA virus evolution

R. Navarro, S. Ambros, A. Butkovic, J. L. Carrasco, R. Gonzalez, F. Martinez, B. Wu, S. F. Elena

This study shows that host immunity differences affect RNA virus evolution rates and patterns, with resistant hosts driving faster adaptation and permissive hosts selecting for specialist viruses.

bioRxiv · Oct 13, 2020Evolutionary Biology

Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy

R. Basar, N. Uprety, E. Ensley, M. Daher, K. Klein, F. Martinez, F. Aung, M. Shanley, B. Hu, E. Gokdemir, M. Mendt, F. Reyes Silva, S. Acharya, T. Laskowski, L. Muniz-Feliciano, , K. Rezvani

The paper expands SARS-CoV-2 T-cells from COVID-19 donors using IL-2/4/7 cytokines, achieving >1000-fold expansion with preserved function, and inactivates the glucocorticoid receptor to create glucocorticoid-resistant T-cells for adoptive therapy.

bioRxiv · Sep 15, 2020Immunology

First report of antiviral activity of nordihydroguaiaretic acid against Fort Sherman-like virus (Orthobunyavirus)

F. Martinez, M. L. Mugas, J. J. Aguilar, J. Marioni, M. S. Contigiani, S. C. Nunez Montota, B. S. Konigheim

This study investigates the antiviral activity of nordihydroguaiaretic acid (NDGA) against Fort Sherman-like virus (FSV-like) and its effects on viral replication and lipid metabolism.

bioRxiv · Aug 4, 2020Microbiology

Diminishing returns of inoculum size on the rate of a plant RNA virus evolution

R. Navarro, S. Ambros, F. Martinez, S. F. Elena

The paper tests if increasing inoculum size reduces evolutionary rate in a plant RNA virus, finding mixed results across fitness traits.

bioRxiv · Nov 28, 2017Evolutionary Biology