Author

S. Brindley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Organism:rat· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. Chatterjee· 2 shared P. Nagpal· 2 shared B. Kusick· 1 shared C. M. Courtney· 1 shared C. R. McCollum· 1 shared J. Brown· 1 shared J. M. Brown· 1 shared J. Moreno· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Chatterjee

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2 papers

Recent·Most cited

Large- and Small-Animal Studies of Safety, Pharmacokinetics (PK), and Biodistribution of Inflammasome-Targeting Nanoligomer in the Brain and Other Target Organs

S. Risen, B. Kusick, S. Sharma, V. Gilberto, S. Brindley, M. Aguilar, J. Brown, S. McGrath, A. Chatterjee, J. Moreno, P. Nagpal

This paper evaluates the safety, pharmacokinetics, and biodistribution of an inflammasome-targeting Nanoligomer cocktail in small and large animals across multiple administration routes.

bioRxiv · Feb 7, 2024Pharmacology & Toxicology

Safety and biodistribution of NanoligomersTM targeting SARS-CoV-2 genome for treatment of COVID-19

C. R. McCollum, C. M. Courtney, N. J. O'Connor, T. R. Aunins, T. X. Jordan, K. Rogers, S. Brindley, J. M. Brown, P. Nagpal, A. Chatterjee

This paper evaluates the safety and biodistribution of a novel Nanoligomer targeting SARS-CoV-2 in mice, showing it is safe, nontoxic, and effectively distributed throughout the body.

bioRxiv · Jul 19, 2022Bioengineering