Author

S. Buchanan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. G. Waks· 1 shared A. S. Walker· 1 shared C. A. Marwick· 1 shared C. Goswami· 1 shared C. P. Yu· 1 shared D. Brown· 1 shared D. Kim· 1 shared D. W. Crook· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. G. Waks

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Author profile →

2 papers

Recent·Most cited

The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors in patients with hormone receptor positive metastatic breast cancer

S. A. Wander, O. Cohen, X. Gong, G. N. Johnson, J. Buendia-Buendia, M. R. Lloyd, D. Kim, F. Luo, P. Mao, K. Helvie, K. J. Kowalski, U. Nayar, A. G. Waks, S. Parsons, R. Martinez, , N. Wagle

The paper identifies eight resistance mechanisms to CDK4/6 inhibitors in HR+ breast cancer, present in 80% of resistant tumors, with potential therapeutic strategies.

bioRxiv · Nov 28, 2019Cancer Biology

A role for tetracycline selection in the evolution of Clostridium difficile PCR-ribotype 078

K. E. Dingle, X. Didelot, T. P. Quan, D. W. Eyre, N. Stoesser, C. A. Marwick, J. Coia, D. Brown, S. Buchanan, U. Z. Ijaz, C. Goswami, G. Douce, W. N. Fawley, M. H. Wilcox, T. E. Peto, , D. W. Crook

The paper investigates the evolutionary history of Clostridium difficile RT078, finding that tetracycline resistance genes, particularly tetM, were acquired independently in multiple clonal expansions, contributing to its increased prevalence.

bioRxiv · Feb 8, 2018Microbiology