P. Mao

Insight into the genetic diversity, resistance, and virulence of Listeria from the marine environment: reveal the risk of hypervirulent isolates

This study examines Listeria species in beach sand, identifying hypervirulent isolates and their potential role in human listeriosis.

A highly attenuated SARS-CoV-2 related pangolin coronavirus variant has a 104nt deletion at the 3'-terminus untranslated region

This study identifies a highly attenuated SARS-CoV-2 related pangolin coronavirus variant with a 104nt deletion in the 3'-UTR HVR, showing reduced virulence in vitro and in vivo.

Comprehensive Analysis of Co-Mutations Identifies Cooperating Mechanisms of Tumorigenesis

The paper analyzes co-mutations across multiple cancer types to identify cooperating mechanisms in tumorigenesis and their clinical implications.

Cell line-specific network models of ER+ breast cancer identify PI3Kα inhibitor sensitivity factors and drug combinations

The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors in patients with hormone receptor positive metastatic breast cancer

The paper identifies eight resistance mechanisms to CDK4/6 inhibitors in HR+ breast cancer, present in 80% of resistant tumors, with potential therapeutic strategies.

Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer

This study identifies FGFR and FGF pathway alterations as acquired resistance mechanisms to ER-targeted therapy in ER+ metastatic breast cancer and suggests targeted inhibitors as potential treatments.