MicrobiologybioRxiv
Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms
M. M. McDonnell, S. C. Karvonen, A. Gaba…·M. Emerman
This paper creates synthetic APOBEC3 proteins with enhanced antiviral activity against HIV-1 through non-catalytic mechanisms, comparable to the most potent natural APOBEC3 variant.
DOI 10.1371/journal.ppat.1009523