BiophysicsbioRxivPreprint
A cationic lipid site at the outward transmembrane face of a pentameric ligand-gated ion channel
A. Sridhar, S. C. R. Lummis, D. Pasini…·C. Ulens
This study identifies a cationic lipid binding site on the outward face of the ELIC pLGIC, supported by simulations and mutagenesis, with implications for lipid modulation and drug design.
DOI 10.1101/2021.03.24.436810