Author

S. Capponi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

S. Bianco· 2 shared A. Catching· 1 shared A. Natale· 1 shared A. Wagner· 1 shared D. Crottes· 1 shared D. L. Minor· 1 shared E. J. Navarro· 1 shared F. Aberemane-Ali· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiophysics

S. Bianco

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3 papers

Recent·Most cited

A tradeoff between enterovirus A71 particle stability and cell entry

A. Catching, M. T. Yeh, S. Bianco, S. Capponi, R. Andino

This study identifies a mutation in enterovirus A71 that increases particle stability but reduces cell entry efficiency, revealing structural changes in the capsid.

bioRxiv · Sep 28, 2022Biophysics

AI-driven prediction of SARS-CoV-2 variant binding trends from atomistic simulations

S. Capponi, S. Wang, E. J. Navarro, S. Bianco

The paper presents an AI method to predict SARS-CoV-2 variant binding affinity trends using atomistic simulations with high accuracy and reduced simulation time.

bioRxiv · Mar 7, 2021Biophysics

K2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions

M. Lolicato, A. Natale, F. Aberemane-Ali, D. Crottes, S. Capponi, R. Duman, A. Wagner, J. M. Rosenberg, M. Grabe, D. L. Minor

This study identifies potassium-dependent conformational changes in K2P2.1 channels that underlie C-type gating, revealing asymmetric order-disorder transitions in the selectivity filter and adjacent loops.

bioRxiv · Mar 20, 2020Biophysics