Author

S. Colombo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Organism:yeast· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. Martegani· 2 shared A. D. Davidson· 1 shared A. E. Marriott· 1 shared A. Kipar· 1 shared A. Owen· 1 shared B. Bonomelli· 1 shared C. Joo· 1 shared D. A. Matthews· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiophysics

E. Martegani

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evidence for noisy oscillations of cAMP under nutritional stress condition in budding yeast

S. Colombo, M. Collini, L. D' Alfonso, G. Chirico, E. Martegani

The paper detects noisy cAMP oscillations in single yeast cells under glucose limitation using a FRET sensor and spectral analysis.

bioRxiv · Jan 23, 2023 · PreprintBiophysics

Mitochondrial active Ras2 protein promotes apoptosis and regulated cell death in a cAMP/PKA pathway-dependent manner in budding yeast.

B. Bonomelli, E. Martegani, S. Colombo

The paper shows that mitochondrial active Ras2 promotes apoptosis via the cAMP/PKA pathway in budding yeast, while Ras1 is involved in pro-survival mechanisms.

bioRxiv · Oct 13, 2021 · PreprintMicrobiology

Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19.

J. J. Clark, R. Penrice-Randal, P. Sharma, A. Kipar, X. Dong, S. Pennington, A. E. Marriott, S. Colombo, A. D. Davidson, M. Kavanagh Williamson, D. A. Matthews, L. Turtle, T. Prince, G. Hughes, E. I. Patterson, , J. P. Stewart

This study shows that sequential infection with influenza A virus followed by SARS-CoV-2 in mice leads to more severe disease and encephalitis compared to single infections.

bioRxiv · Oct 13, 2020 · PreprintMicrobiology

Selective Prespacer Processing Ensures Precise CRISPR-Cas Adaptation

S. Kim, L. Loeff, S. Colombo, S. Brouns, C. Joo

This study identifies how Cas1-Cas2 selects and processes prespacers for CRISPR-Cas adaptation using single-molecule fluorescence and DnaQ exonucleases.

bioRxiv · Apr 16, 2019Biophysics