Author

S. E. Howden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:organoid / primary culture· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. M. Vanslambrouck· 2 shared K. S. Tan· 2 shared K. T. Lawlor· 2 shared M. H. Little· 2 shared A. Chambon· 1 shared A. E. Chen· 1 shared A. Hartung· 1 shared A. Hill· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioengineering

J. M. Vanslambrouck

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Author profile →

3 papers

Recent·Most cited

Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization, and de novo cell types

J. C. Maggiore, R. LeGraw, A. Przepiorski, J. Velazquez, C. Chaney, E. Streeter, A. Silva-Barbosa, J. Franks, J. Hislop, A. Hill, H. Wu, K. Pfister, S. E. Howden, S. C. Watkins, M. Little, , N. A. Hukriede

This paper genetically engineers an endothelial niche in human kidney organoids to enhance vascularization, maturation, and the emergence of new cell types.

bioRxiv · May 30, 2023Bioengineering

Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids

J. M. Vanslambrouck, S. B. Wilson, K. S. Tan, E. Groenewegen, R. Rudraraju, J. Neil, K. T. Lawlor, S. Mah, M. Scurr, S. E. Howden, K. Subbarao, M. H. Little

This paper enhances kidney organoid maturation to produce functional proximal tubules, enabling better toxicity screening and infectious disease modeling.

bioRxiv · Oct 14, 2021 · PreprintBioengineering

Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening.

J. W. Higgins, A. Chambon, K. Bishard, A. Hartung, D. Arndt, J. Brugnano, P. Xuan Er, K. T. Lawlor, J. M. Vanslambrouck, S. Wilson, A. N. Combes, S. E. Howden, K. S. Tan, S. V. Kumar, L. J. Hale, , M. H. Little

The paper demonstrates the use of bioprinted kidney organoids for high content drug screening, showing reproducibility and response to doxorubicin toxicity.

bioRxiv · Dec 23, 2018 · PreprintCell Biology