Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties
J. H. Shin, J. Park, J. Lim, J. Jeong, R. K. Dinesh, S. E. Maher, J. Kim, S. Park, J. Y. Hong, J. Wysolmerski, J. Choi, A. L. M. Bothwell
This study shows DKK2 is required for colon cancer metastasis by generating cancer cells with Paneth cell properties through HNF4A regulation.
bioRxiv · Apr 12, 2024Cancer Biology