PhysiologybioRxiv
Redefining Interleukin 11 as a regeneration-limiting hepatotoxin
A. A. Widjaja, J. R. Dong, E. Adami…·S. A. Cook
This study reveals IL11 as a hepatotoxin that limits liver regeneration after APAP overdose, showing its inhibition of endogenous IL11 activity protects mice.
DOI 10.1126/scitranslmed.aba8146