Author

S. H. Leppla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Gangwal· 1 shared A. P. Pomerantsev· 1 shared C. c. keshavam· 1 shared C. Merritt· 1 shared D. Paliga· 1 shared E. M. Chun· 1 shared L. K. Singh· 1 shared M. Gupta· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Gangwal

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2 papers

Recent·Most cited

MicrobiologyJournal of BacteriologyPeer-reviewedMay 7, 2021

Bacillus anthracis chain length, a virulence determinant, is regulated by a transmembrane Ser/Thr protein kinase PrkC

M. Gupta, Y. Singh, N. Dhasmana…·S. H. Leppla

This study identifies PrkC, a transmembrane Ser/Thr kinase in B. anthracis, as a regulator of bacterial chain length, which impacts virulence and pathophysiological outcomes.

DOI 10.1128/jb.00582-20

bacteria (other)proteomics

𝕏 PostBluesky

PathologybioRxivPreprintJan 22, 2021

Direct imaging of anthrax intoxication in animals reveals shared and individual functions of CMG-2 and TEM-8 in cellular toxin entry

C. Merritt, E. M. Chun, R. J. Fattah…·T. H. Bugge

The paper develops a live animal imaging assay to visualize anthrax toxin entry via CMG-2 and TEM-8, revealing tissue-specific receptor functions.

DOI 10.1101/2021.01.22.427304

mouseimaging

𝕏 PostBluesky