Author

S. Holst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Wuhrer· 2 shared T. Zhang· 2 shared A. A. de Waard· 1 shared A. Mulder· 1 shared A. Schlitzer· 1 shared A. Xagara· 1 shared B. Cabukusta· 1 shared B. Schraml· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

M. Wuhrer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses

H. Xiao, I. Ulmert, L. Bach, J. Huber, H. Narasimhan, I. Kurochkin, Y. Chang, S. Holst, U. Moerbe, L. Zhang, A. Schlitzer, F. Pereira, B. Schraml, D. Baumjohann, K. Lahl

bioRxiv · Aug 10, 2022Immunology

Dissection of N-, O- and glycosphingolipid glycosylation changes in PaTu-S pancreatic adenocarcinoma cells upon TGF-β challenge

J. Zhang, Z. Zhang, S. Holst, C. BlÖchl, K. Madunic, M. Wuhrer, P. ten Dijke, T. Zhang

This study examines how TGF-β affects glycosylation patterns in pancreatic cancer cells, identifying N-glycome changes linked to SOX4 expression and SMAD4 deficiency.

bioRxiv · May 14, 2021 · PreprintCancer Biology

The SPPL3-defined glycosphingolipid repertoire regulates immune responses by improving HLA class I access

M. L. M. Jongsma, M. Raaben, A. A. de Waard, T. Zhang, B. Cabukusta, R. Platzer, V. A. Blomen, A. Xagara, T. Verkerk, S. Bliss, L. Janssen, E. Stickel, S. Holst, R. Plomp, A. Mulder, , R. M. Spaapen

The paper identifies a glycosphingolipid (GSL) signature that inhibits HLA-I antigen presentation and shows its reversal by clinically approved drugs.

bioRxiv · Sep 26, 2020Immunology