Author

S. Hsu

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Celia R. Espinoza· 2 shared Gajanan Dattatray KatkariD· 2 shared Kennith Carpio-Perkins· 2 shared Madhubanti MullickiD· 2 shared Mahitha Shree AnandachariD· 2 shared Megan L. Estanol· 2 shared Pradipta GhoshiD· 2 shared Saptarshi SinhaiD· 2 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Celia R. Espinoza

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A NOD2-Encoded Toggle Switch Resolves the Host-Microbe Battle Over Cyclic AMP Control

Mahitha Shree Anandachar, David Chen, Kennith Carpio-Perkins, Gajanan Dattatray Katkar, Suchismita Roy, Celia R. Espinoza, Madhubanti Mullick, Saptarshi Sinha, Michelle Nakayama, Jasmin Salem, Megan L. Estanol, Rishav Bhattacharjee, Kameron M. Zablan, S. Hsu, Sinclair Williams, , Pradipta Ghosh

This paper identifies a host-encoded toggle switch involving NOD2 and GIV that controls cAMP levels in macrophages, converting tolerant cells into microbicidal machines to restore microbial clearance and gut barrier integrity.

bioRxiv · Mar 31, 2026 · PreprintImmunology

Distinct Colitis-Associated Macrophages Drive NOD2-Dependent Bacterial Sensing and Gut Homeostasis

Gajanan Dattatray Katkar, Mahitha Shree Anandachar, Stella‐Rita Ibeawuchi, Ella McLaren, Megan L. Estanol, Kennith Carpio-Perkins, S. Hsu, Celia R. Espinoza, Jane Coates, Yashaswat S. Malhotra, Madhubanti Mullick, Vanessa Castillo, Daniella T. Vo, Saptarshi Sinha, Pradipta Ghosh

The paper identifies niColAMs as critical for IBD recovery and shows GIV-NOD2 interaction is essential for microbial sensing and gut homeostasis.

Journal of Clinical Investigation · Oct 2, 2025Peer-reviewedImmunology

Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure with Pulmonary Hypertension

V. Jani, M. I. Aslam, A. J. Fenwick, W. Ma, H. Gong, G. Milburn, D. Nissen, I. M. Cubero Salazar, O. Hanselman, M. Mukherjee, M. K. Halushka, K. B. Margulies, K. Campbell, T. C. Irving, D. A. Kass, S. Hsu

This study identifies contractile deficits in right ventricular myocytes of HFrEF-PH patients, showing reduced calcium-activated tension and altered myosin ATP turnover, with implications for targeted therapies.

bioRxiv · Mar 9, 2023Biophysics

The Five-Primer Challenge: An inquiry-based laboratory module for synthetic biology

S. Hsu, J. Huenemann, V. Kulkarni, R. Amaro, R. Moseley, N. Mukhitov, R. Tiwari, S. Wang, M. J. Smanski

This paper describes an inquiry-based laboratory module for synthetic biology where students design DNA sequences to maximize GFP expression using DNA assembly techniques.

bioRxiv · Aug 28, 2019 · PreprintScientific Communication & Education