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S. J. Miner

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

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A. M. Chinnaiyan· 1 shared A. Parolia· 1 shared C. Abbineni· 1 shared C. R. Vakoc· 1 shared E. Young· 1 shared F. Su· 1 shared H. Zheng· 1 shared J. C.-Y. Tien· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperCancer Biology

A. M. Chinnaiyan

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1 paper

Recent·Most cited

Cancer BiologybioRxivJan 22, 2024

Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies

T. He, L. Xiao, Y. Qiao…·A. M. Chinnaiyan

This study identifies a therapeutic vulnerability in POU2F-POU2AF-driven cancers by showing that targeting the mSWI/SNF complex with a PROTAC degrader reduces tumor growth in preclinical models.

DOI 10.1016/j.ccell.2024.06.006

humanbulk RNA-seq

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