S. K. Sarkar

This paper quantifies allosteric communications in MMP1 on alpha-synuclein aggregates using FRET and virtual screening, showing substrate-dependent changes in ligand-binding sites.

This study investigates how inter-domain dynamics of MMP1 correlate with its fibrinolytic activity using single-molecule FRET and kinetic modeling.

This paper identifies functionally relevant inter-domain dynamics in MMP1 on collagen fibrils, showing that open conformations correlate with activity and can be modulated by mutations and ligands.

This study shows cephalosporins inhibit quorum sensing and virulence in Pseudomonas aeruginosa, improving survival in C. elegans.

The paper quantifies cellular distribution randomness in a 3D matrix using a multiview light-sheet microscope and Poisson process modeling, showing agreement between simulations and experiments.