TOMM40 regulates hepatocellular and plasma lipid metabolism via an LXR-dependent pathway
N. V. Yang, J. Y. Chao, K. A. Garton, T. Tran, S. King, J. Orr, J. H. Oei, M. Kang, R. Zalpuri, D. M. Jorgens, P. Konchadi, J. S. Chorba, E. Theusch, R. M. Krauss
This study shows that TOMM40 regulates lipid metabolism in hepatocytes through an LXR-dependent pathway, affecting plasma lipid levels and hepatic lipid droplet accumulation.
bioRxiv · Jun 27, 2024Cell Biology