Author

A. Law

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:chicken / avian· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

B. Whitelaw· 2 shared E. Rong· 2 shared I. Dry· 2 shared R. Dalziel· 2 shared S. Lillico· 2 shared W. S. Tan· 2 shared A. C. Ravicahandran· 1 shared A. Corla· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

B. Whitelaw

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Synthetic antigen presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses.

P. F. Cespedes, A. K. Jainarayanan, L. Fernandez-Messina, S. Valvo, D. G. Saliba, A. Kvalvaag, L. Chen, E. Kurz, C. Ganskow, H. Colin-York, M. Fritzsche, P. Yanchun, T. Dong, E. Johnson, J. A. Siller-Farfan, , M. L. Dustin

This study uses synthetic antigen-presenting cells to analyze the composition and functional specialization of extracellular vesicles released during T cell immunological synapses.

bioRxiv · May 29, 2021 · PreprintImmunology

A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong

J. Flannery, B. Shih, I. R. Haga, M. Ashby, A. Corla, S. King, G. L. Freimanis, N. Polo, A. Tse, C. Brackman, J. Chan, P. Pun, A. D. Ferguson, A. Law, S. J. Lycett, , P. Beard

This paper reports the first detection of lumpy skin disease virus in Hong Kong, identifying a novel strain genetically distinct from previous outbreaks.

bioRxiv · Apr 20, 2021Microbiology

Host cell factors important for BHV-1 cell entry revealed by genome-wide CRISPR knockout screen

W. S. Tan, E. Rong, I. Dry, S. Lillico, A. Law, B. Whitelaw, R. Dalziel

The paper identifies host factors critical for BHV-1 entry using CRISPR knockout screens and validates them with a new CRISPRi system.

bioRxiv · Jun 18, 2020 · PreprintMicrobiology

Genome-wide CRISPR knockout screen reveals membrane tethering complexes EARP and GARP important for Bovine Herpes Virus Type 1 replication

W. S. Tan, E. Rong, I. Dry, S. Lillico, A. Law, B. Whitelaw, R. Dalziel

The paper uses a genome-wide CRISPR knockout screen to identify host genes important for Bovine Herpes Virus Type 1 replication, finding that EARP and GARP membrane tethering complexes are critical for viral replication.

bioRxiv · Jun 17, 2020 · PreprintMicrobiology

Structural and Functional analysis of the GABARAP Interaction Motif (GIM).

V. V. Rogov, A. Stolz, A. C. Ravicahandran, A. Law, H. Suzuki, A. Kniss, D. O. Rios-Szwed, F. Loehr, S. Wakatsuki, V. Doetsch, I. Dikic, R. C. J. Dobson, D. McEwan

The paper identifies a GABARAP-specific interaction motif (GIM) and demonstrates its selectivity over LC3 using biophysical and structural analyses.

The EMBO Reports · Aug 1, 2017Peer-reviewedBiochemistry