Cellular Heterogeneity of Pluripotent Stem Cell Derived Cardiomyocyte Grafts is Mechanistically Linked to Treatable Arrhythmias
D. Selvakumar, Z. E. Clayton, A. Prowse, S. Dingwall, J. George, H. Shah, S. Chen, R. D. Hume, L. Tjahjadi, S. Igoor, R. J. P. Skelton, A. Hing, H. Paterson, S. L. Foster, L. Pearson, , J. J. H. Chong
This study identifies arrhythmogenic subpopulations in pluripotent stem cell-derived cardiomyocytes and shows that combination therapy and catheter ablation can reduce engraftment arrhythmias.
bioRxiv · Sep 15, 2022 · PreprintCell Biology