Author

S. L. Houlihan

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

B. Bosbach· 1 shared C.-C. Chen· 1 shared D. F. Tschaharganeh· 1 shared D. Requena· 1 shared E. R. Kastenhuber· 1 shared G. Lalazar· 1 shared J. E. Wilkinson· 1 shared S. M. Simon· 1 shared

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2017-2017 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

B. Bosbach

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 21, 2017

DNAJB1-PRKACA fusion kinase interacts with β-catenin and liver regenerative response to drive fibrolamellar hepatocellular carcinoma

E. R. Kastenhuber, G. Lalazar, D. F. Tschaharganeh…·S. W. Lowe

This study shows that the DNAJB1-PRKACA fusion kinase drives fibrolamellar hepatocellular carcinoma in mice and identifies β-catenin activation and environmental factors as contributors to tumor progression.

DOI 10.1073/pnas.1716483114

mousegenetic perturbation / CRISPR

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