ImmunologybioRxiv
IgD+ Age-Associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged
O. A. Kugler-Umana, W. Zhang, Y. Kuang…·S. L. Swain
The paper identifies IgD+CD21-CD23- age-associated B cells as precursors of infection-induced B cells in aged mice, which provide protective antibody responses and can be induced by inactivated vaccines.
DOI 10.1111/acel.13705