Author

S. Ladigan

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

A. Tannapfel· 1 shared A. Wiegard· 1 shared C. Kutter· 1 shared C. Teschendorf· 1 shared D. P. Cameron· 1 shared D. Vangala· 1 shared E. Iliopoulou· 1 shared H. Benredjem· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Tannapfel

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1 paper

Recent·Most cited

Cancer BiologybioRxivFeb 10, 2023

Co-inhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription

D. P. Cameron, J. Grosser, S. Ladigan…·L. Baranello

The paper shows that combining TOP1 and BRD4 inhibitors selectively kills pancreatic cancer cells by inducing readthrough transcription, without harming normal cells.

DOI 10.1126/sciadv.adg5109

mousebulk RNA-seq

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