Cancer BiologybioRxiv
Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy
T. G. Krieger, S. LeBlanc-Soto, J. Jabs…·C. Conrad
The paper uses single-cell RNA sequencing to analyze PDAC organoids and identifies conserved cell states and a differentiation hierarchy linked to tumor subtypes.