Author

S. Linder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cancer & tumor microenvironment· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

W. Zwart· 3 shared A. M. Bergman· 2 shared A. A. Hamid· 1 shared A. Alimonti· 1 shared A. Disanza· 1 shared A. G. Sowalsky· 1 shared A. Mutti· 1 shared A. Rinaldi· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersCancer Biology

W. Zwart

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Loss of tristetraprolin activates NF-κB induced phenotypic plasticity and primes transition to lethal prostate cancer

K. L. Morel, A. A. Hamid, B. G. Falcon, J. N. Singh, S. Linder, A. M. Bergman, H. G. van der Poel, I. Hofland, E. M. Bekers, S. Trostel, S. Wilkinson, A. T. Ku, D. L. Burkhart, M. Kim, J. Kim, , L. Ellis

This study shows that loss of ZFP36 promotes NF-κB activation and phenotypic plasticity in prostate cancer, leading to aggressive disease and castration resistance, which can be reversed by NF-κB inhibition.

bioRxiv · Aug 5, 2022 · PreprintCancer Biology

Targeting Mitochondrial Metabolism in Clear Cell Carcinoma of the Ovaries

M. Bazzaro, S. Linder, M. Shetty, X. Zhang, V. Clemente

This study shows that loss of ARID1A increases mitochondrial metabolism in OCCC and that inhibiting mitochondrial complex I improves survival in preclinical models.

bioRxiv · Feb 17, 2021Cancer Biology

Cargo-specific recruitment in clathrin and dynamin-independent endocytosis

P. Moreno-Layseca, N. Z. Jäntti, R. Godbole, C. Sommer, G. Jacquemet, H. Al-Akhrass, P. Kronqvist, R. E. Kallionpaa, L. Oliveira-Ferrer, P. Cervero, S. Linder, M. Aepfelbacher, J. Rae, R. G. Parton, A. Disanza, , J. Ivaska

The paper identifies swiprosin-1 as a cargo-specific adaptor for the CG-pathway, showing its role in integrin internalization and breast cancer progression.

bioRxiv · Oct 5, 2020Cell Biology

Functional mapping of androgen receptor enhancer activity

C.-C. F. Huang, S. Lingadahalli, T. Morova, D. Ozturan, E. Hu, I. P. L. Yu, S. Linder, M. Hoogstraat, S. Stelloo, F. Sar, H. van der Poel, U. B. Altintas, M. Saffarzadeh, S. Le Bihan, B. McConeghy, , N. A. Lack

The paper functionally maps AR enhancer activity using STARRseq, finding most AR binding sites are inactive or constitutively active, with inducible enhancers forming regulatory hubs that drive gene transcription.

bioRxiv · Aug 18, 2020Cancer Biology

Dual Functions of SPOP and ERG Dictate Androgen Therapy Responses in Prostate Cancer

T. Bernasocchi, G. El tekle, M. Bolis, A. Mutti, A. Vallerga, L. P. Brandt, F. Spriano, T. Svinkina, M. Zoma, V. Ceserani, A. Rinaldi, H. Janouskova, D. Bossi, M. Cavalli, S. Mosole, , J. P. P. Theurillat

This study shows that SPOP and ERG mutations in prostate cancer have opposing effects on androgen receptor signaling and therapy response.

bioRxiv · Jul 8, 2020Cancer Biology