C. Sommer

Super-resolution expansion microscopy in plant roots

This study develops and applies expansion microscopy to Arabidopsis root tissues, achieving improved resolution and visualizing subcellular structures.

User-friendly electron microscopy protocols for the visualization of biological macromolecular complexes in three dimensions: Visualization of planta clathrin-coated vesicles at ultrastructural resolution

The paper presents user-friendly electron microscopy protocols for visualizing plant clathrin-coated vesicles in 3D at nanometer resolution, along with a deep learning workflow for analysis.

In vitro reconstitution of divisome activation

This study uses biochemical and imaging methods to investigate how FtsA activates the bacterial divisome by switching between polymer and monomer states, revealing its role in FtsZ dynamics and FtsN recruitment.

The hepatocyte insulin receptor is required to program rhythmic gene expression and the liver clock

This study investigates the role of the hepatocyte insulin receptor in regulating circadian gene expression and liver clock function in adult mice.

Cargo-specific recruitment in clathrin and dynamin-independent endocytosis

The paper identifies swiprosin-1 as a cargo-specific adaptor for the CG-pathway, showing its role in integrin internalization and breast cancer progression.

Computational analysis of filament polymerization dynamics in cytoskeletal networks

The paper introduces an automated image analysis workflow to study polymerization dynamics of cytoskeletal filaments using time-lapse microscopy data.

A Deep Learning And Novelty Detection Framework For Rapid Phenotyping In High-Content Screening

CellCognition Explorer uses deep learning and novelty detection to rapidly phenotype high-content screening data without prior phenotype knowledge or user training.