BiophysicsPNAS NexusPeer-reviewed
Dilated cardiomyopathy mutation in beta-cardiac myosin enhances actin activation of the power stroke and phosphate release
S. M. Bodt, J. Ge, W. Ma…·C. M. Yengo
This paper investigates how the E525K mutation in beta-cardiac myosin affects actin activation, power stroke, and phosphate release, revealing structural and kinetic changes linked to dilated cardiomyopathy.
DOI 10.1093/pnasnexus/pgae279