BiochemistrybioRxiv
Cryo-EM Structures of HIV-1 trimer bound to CD4-mimetics M48U1 and BNM-III-170 adopt a CD4-bound open conformation
C. A. Jette, C. O. Barnes, S. M. Kirk…·P. J. Bjorkman
The paper presents cryo-EM structures of HIV-1 Env trimers bound to CD4-mimetics, showing conformational changes induced by Phe43 pocket binding.