Cell BiologybioRxiv
Dihydroxyacetone phosphate signals glucose availability to mTORC1
J. M. Orozco, P. A. Krawczyk, S. M. Scaria…·D. Sabatini
This study identifies dihydroxyacetone phosphate (DHAP) as the glucose-derived metabolite that activates mTORC1, linking glucose availability to cell growth regulation.
DOI 10.1038/s42255-020-0250-5