Author

S. M. Soucy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. E. Goen· 1 shared A. Jiang· 1 shared A. L. Johnson· 1 shared A. M. Roberts· 1 shared B. A. Romo· 1 shared E. Demidenko· 1 shared E.-C. K. Duffy· 1 shared F. Kolling· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. E. Goen

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3 papers

Recent·Most cited

Cancer BiologybioRxivMar 16, 2023

Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer

N. A. Traphagen, G. N. Schwartz, S. Tau…·T. W. Miller

This study shows estrogen therapy induces DNA damage in ER+ breast cancer cells, which can be enhanced by PARP inhibition to improve treatment outcomes.

DOI 10.1158/1078-0432.ccr-23-0488

humanDNA methylation

𝕏 PostBluesky

Evolutionary BiologybioRxivPreprintOct 16, 2020

Non-phylogenetic identification of co-evolving genes for reconstructing the archaeal Tree of Life

L. T. Rangel, S. M. Soucy, J. C. Setubal…·G. P. Fournier

This paper introduces the Evolutionary Similarity Index (IES) to identify co-evolving gene families in archaea, finding eight major clusters with compatible evolutionary trends and evidence of horizontal gene transfer.

DOI 10.1101/2020.10.16.343293

proteomicsstatistical model

𝕏 PostBluesky

Evolutionary BiologybioRxivOct 29, 2017

Insights into Origin and Evolution of α-proteobacterial Gene Transfer Agents

M. Shakya, S. M. Soucy, O. Zhaxybayeva

This study investigates the origin and evolution of RcGTA in α-proteobacteria, finding that it co-evolves with host chromosomes and is not an atypical or defective virus.

DOI 10.1093/ve/vex036

bacteria (other)statistical model

𝕏 PostBluesky