Author

S. Mandrup

Primary ORCID profile (0000-0002-0961-5787 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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S. MandrupiD3 papers · Broad Institute

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Upadhyaya· 1 shared B. K. Pedersen· 1 shared C. H. Hahn· 1 shared C. Scheele· 1 shared D. A. Stavreva· 1 shared D. M. Presman· 1 shared D. Wüstner· 1 shared E. S. Andersen· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Upadhyaya

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Author profile →

2 papers

Recent·Most cited

Single-molecule tracking reveals two low-mobility states for chromatin and transcriptional regulators within the nucleus

K. Wagh, D. A. Stavreva, R. A. Jensen, V. Paakinaho, G. Fettweis, R. L. Schiltz, D. Wüstner, S. Mandrup, D. M. Presman, A. Upadhyaya, G. L. Hager

This study uses single-molecule tracking and machine learning to identify two low-mobility states of chromatin and transcriptional regulators, showing dynamic interactions and switching between states.

bioRxiv · Jul 25, 2022Biophysics

Thermogenic genes are blunted whereas brown adipose tissue identity is preserved in human obesity

N. Z. Jespersen, M. W. Andersen, V. H. Jensen, T. W. Staerker, M. C. Severinsen, L. Peijs, R. Soares, I. Forss, E. S. Andersen, C. H. Hahn, P. Homee, S. Mandrup, B. K. Pedersen, S. Nielsen, C. Scheele

The paper identifies a reduction in thermogenic genes but preserved brown adipose tissue identity in human obesity through transcriptomic analysis of BAT and WAT.

bioRxiv · May 7, 2020 · PreprintCell Biology