Author

B. K. Pedersen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

S. Nielsen· 4 shared C. Scheele· 3 shared N. Z. Jespersen· 3 shared L. Peijs· 2 shared R. Soares· 2 shared A. B. Klein· 1 shared A. M. Fritzen· 1 shared A. S. Deshmukh· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersPhysiology

S. Nielsen

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Author profile →

5 papers

Recent·Most cited

Exercise Training Remodels Adipocyte-Specific Extracellular Matrix Proteins and Alters Innervation and Vascularization in Inguinal White Adipose Tissue (iWAT)

P. Nigro, M. Vamvini, J. J. Yang, T. Caputo, L.-L. Ho, D. Papadopoulos, N. P. Carbone, R. Colin, J. He, H. F. Michael, J. D. White, J. Robidoux, R. Hickner, S. Nielsen, B. K. Pedersen, , L. J. Goodyear

This study shows that exercise training remodels iWAT ECM, increases vascularization and innervation, and alters adipocyte subpopulations in male mice.

bioRxiv · Aug 9, 2022Physiology

Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

A. B. Klein, T. S. Nicolaisen, N. Ortenblad, K. D. Gejl, R. Jensen, A. M. Fritzen, E. L. Larsen, K. Karstoft, H. E. Poulsen, T. Morville, R. E. Sahl, J. W. Helge, J. Lund, S. Falk, M. Lyngbaek, , C. Clemmensen

The paper shows that exercise increases circulating GDF15 levels, but this physiological increase does not suppress appetite or exercise motivation like pharmacological GDF15.

bioRxiv · Oct 23, 2020Physiology

Thermogenic genes are blunted whereas brown adipose tissue identity is preserved in human obesity

N. Z. Jespersen, M. W. Andersen, V. H. Jensen, T. W. Staerker, M. C. Severinsen, L. Peijs, R. Soares, I. Forss, E. S. Andersen, C. H. Hahn, P. Homee, S. Mandrup, B. K. Pedersen, S. Nielsen, C. Scheele

The paper identifies a reduction in thermogenic genes but preserved brown adipose tissue identity in human obesity through transcriptomic analysis of BAT and WAT.

bioRxiv · May 7, 2020 · PreprintCell Biology

Proteomics-based comparative mapping of the human brown and white adipocyte secretome reveals EPDR1 as a novel batokine

A. S. Deshmukh, L. Peijs, S. Nielsen, R. Bayarri-Olmos, T. J. Larsen, N. Z. Jespersen, H. Hattel, B. Holst, P. Garred, M. Tang-Christensen, A. Sanfridson, Z. Gerhart-Hines, B. K. Pedersen, M. Mann, C. Scheele

The paper compares the secretomes of human brown and white adipocytes using proteomics, identifying EPDR1 as a novel batokine involved in thermogenesis and energy consumption.

bioRxiv · Aug 30, 2018Physiology

A long-non-coding RNA, LINC00473, confers the human adipose tissue thermogenic phenotype through enhanced cAMP responsiveness.

K.-V. Tran, C. Nandrup-Bus, T. DeSouza, R. Soares, N. Z. Jespersen, S. Y. Min, R. Rojas-Rodriguez, H. Willenbrock, T. Juhlin, M. C. K. Severinsen, K. Malka, B. K. Pedersen, T. Fitzgibbons, C. Scheele, S. Corvera, S. Nielsen

This study identifies LINC00473 as a key regulator of thermogenic adipocyte function, showing its role in enhancing cAMP responsiveness and mitochondrial activity.

bioRxiv · Jun 5, 2018Cell Biology