Author

S. Markowitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1

Frequent Co-Authors

A. R. Morton· 1 shared A. Saiakhova· 1 shared A. Vaziri-Gohar· 1 shared C. F. Bartels· 1 shared D. N. Wald· 1 shared D. Neu· 1 shared E. Ojo· 1 shared E. S. Hong· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. R. Morton

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Author profile →

2 papers

Recent·Most cited

Liver Endothelium Promotes HER3-mediated Cell Survival in KRAS Wild-type and Mutant Colorectal Cancer Cells

M. Rathore, M. Wright, R. Bhattacharya, F. Fan, A. Vaziri-Gohar, J. Winter, Z. Wang, S. Markowitz, J. Willis, L. Ellis, R. Wang

The paper shows liver endothelial cells promote HER3-mediated survival in KRAS wild-type and mutant colorectal cancer cells through secreted factors, suggesting HER3 as a therapeutic target regardless of KRAS mutation status.

bioRxiv · Apr 27, 2021 · PreprintCancer Biology

Mismatch-repair signature mutations activate gene enhancers across colorectal cancer epigenomes

S. Hung, A. Saiakhova, Z. Faber, C. F. Bartels, D. Neu, I. Bayles, E. Ojo, E. S. Hong, W. D. Pontius, A. R. Morton, R. Liu, M. F. Kalady, D. N. Wald, S. Markowitz, P. C. Scacheri

The paper identifies MMR signature mutations in colorectal cancer that activate enhancers by increasing FOX factor affinity and promoting tumor growth.

bioRxiv · Sep 7, 2018Cancer Biology