A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia
V. da Silva-Diz, B. Cao, O. Lancho, E. Chiles, A. Alasadi, S. Luo, D. Augeri, S. Minuzzo, S. Indraccolo, X. Su, S. Jin, D. Herranz
This study shows that MB1-47, a mitochondrial uncoupling compound, effectively inhibits T-ALL cell proliferation and extends survival in mouse models without toxicities.
bioRxiv · Jun 23, 2020Cancer Biology