Author

S. N. Grellscheid

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:microscopy & imaging analysis· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. M. Jones· 2 shared H. Kusumaatmaja· 2 shared T. Stevenson· 2 shared A. Bellanger· 1 shared A. Brech· 1 shared A. Jain· 1 shared A. V. R. Lake· 1 shared B. Basu· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

C. M. Jones

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4 papers

Recent·Most cited

An integrated RNA-proteomic landscape of drug induced senescence in a cancer cell line

F. Görtler, M. Al-Roshdi, S. N. Grellscheid, T. Stevenson

This study provides an integrative multi-omic analysis of proteomic and RNA-seq data from proliferating and senescent osteosarcoma cells to characterize drug-induced senescence.

bioRxiv · Mar 21, 2023 · PreprintCell Biology

Using Shape Fluctuations to Probe the Mechanics of Stress Granules

J. O. Law, C. M. Jones, T. M. Stevenson, M. S. Turner, H. Kusumaatmaja, S. N. Grellscheid

This study introduces a high-throughput flicker spectroscopy technique to measure surface tension in stress granules, revealing deviations from simple liquid droplet behavior.

bioRxiv · May 3, 2022 · PreprintCell Biology

Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies.

A. V. R. Lake, C. E. L. Smith, S. Natarajan, B. Basu, S. K. Best, T. Stevenson, R. Trowbridge, S. N. Grellscheid, J. Bond, R. Foster, C. A. Johnson

The paper identifies ROCK2 as a therapeutic target for ciliopathies through drug and siRNA screens, showing ROCK2 inhibitors could treat cystic kidney disease.

bioRxiv · Nov 26, 2020Cell Biology

Unrestrained ESCRT-III drives chromosome fragmentation and micronuclear catastrophe

M. Vietri, S. W. Schultz, A. Bellanger, C. M. Jones, C. Raiborg, E. Skarpen, C. R. J. Pedurupillay, E. Kip, R. Timmer, A. Jain, P. Collas, R. L. Knorr, S. N. Grellscheid, H. Kusumaatmaja, A. Brech, , C. Campsteijn

This study shows that unrestrained ESCRT-III activity at micronuclei causes chromosome fragmentation and DNA damage, while it facilitates repair in primary nuclei.

bioRxiv · Jan 10, 2019Cell Biology