JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes
K. W. Tan, V. Nähse, C. Campsteijn, A. Brech, K. O. Schink, H. Stenmark
This study identifies JIP4 and Phafin2 as components of a tubular recycling pathway from macropinosomes, showing JIP4 recruitment via Phafin2's PtdIns3P binding.
bioRxiv · Sep 29, 2020Cell Biology