S. R. Azar

This study develops murine models of Ilheus virus infection and shows Aedes mosquitoes are highly susceptible, suggesting ILHV is poised for emergence in the neotropics.

This study investigates immunological trade-offs in non-human primate hosts for dengue and Zika viruses, finding that higher viral replication correlates with increased transmission but reduced antibody response.

This study identifies four mutations in Zika virus that reversed prior mutations, restoring fitness for urban transmission and increasing epidemic risk before the virus spread to the Americas.

This study investigates resistance to fluoroquinolones in dengue virus serotype 4 and finds that resistance mutations affect viral fitness and binding/entry mechanisms.

This study shows fluoroquinolones like enoxacin inhibit flavivirus replication in human cells and reduce ZIKV titer in mouse testes.