Cell BiologybioRxiv
Heterogeneous transcriptome response to DNA damage at single cell resolution.
S. R. Park, S. Namkoong, Z. Z. Zhang…·J. H. Lee
The paper shows that DNA damage induces heterogeneous transcriptome responses in cancer cells, with distinct transcriptional programs dictating cell fate outcomes such as checkpoint, apoptosis, or chemoresistance.
DOI 10.1016/j.celrep.2020.108077